Title
Predictors of adverse pregnancy outcomes in women infected with HIV in Latin America and the Caribbean: A cohort study
Date Issued
01 November 2014
Access level
open access
Resource Type
journal article
Author(s)
Kreitchmann R.
Li S.X.
Melo V.H.
Fernandes Coelho D.
Watts D.H.
Joao E.
Coutinho C.M.
Siberry G.K.
Abstract
Results: Among 1512 women, 1.9% (95% confidence interval, 95% CI, 1.3-2.7) of singleton pregnancies resulted in a stillbirth and 32.9% (95% CI 30.6-35.4) had at least one adverse pregnancy outcome. Of 1483 singleton live births, 19.8% (95% CI 17.8-21.9) were PT, 14.2% (95% CI 12.5-16.1) were LBW, 12.6% (95% CI 10.9-14.4) were SGA, and 0.4% (95% CI 0.2-0.9) of infants died within 28 days of birth. Multivariable logistic regression modelling indicated that the following risk factors increased the probability of having one or more adverse pregnancy outcomes: lower maternal body mass index at delivery (odds ratio, OR, 2.2; 95% CI 1.4-3.5), hospitalisation during pregnancy (OR 3.3; 95% CI 2.0-5.3), hypertension during pregnancy (OR 2.7; 95% CI 1.5-4.8), antiretroviral use at conception (OR 1.4; 95% CI 1.0-1.9), and tobacco use during pregnancy (OR 1.7; 95% CI 1.3-2.2). The results of fitting multivariable logistic regression models for PT, LBW, SGA, and SB are also reported.
Start page
1501
End page
1508
Volume
121
Issue
12
Scopus EID
2-s2.0-84914670299
PubMed ID
Source
BJOG: An International Journal of Obstetrics and Gynaecology
Resource of which it is part
BJOG: An International Journal of Obstetrics and Gynaecology
ISSN of the container
14700328
Source funding
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Sources of information: Directorio de Producción Científica Scopus