After first reexamining Ortega’s philosophy of technique and Quintanilla’s philosophy of technology, this article will propose a philosophy of technoscience that distinguishes between different scales in present-day technological worlds. There are macro-, meso-, micro-, and nano-cosmic scale technoworlds whose properties and structures are still being researched by contemporary technosciences. The philosophy of technology needs to be specific for each kind of world under study, including the social worlds, not only those of nature or the biosphere. An important example in this respect comprises technopersons, artificial entities that superimpose themselves on physical and legal persons and interact in today’s major technoworld: the digital world. At the end of the article, some of the possible consequences and risks of the expansion of the information and communications technologies (ICTs) to microcosms and nanocosms, specifically, to the human brain, will be highlighted.