Title
Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications
Date Issued
01 November 2012
Access level
metadata only access
Resource Type
journal article
Author(s)
Ravindra S.
Mulaba-Bafubiandi A.F.
Rajinikanth V.
Narayana Reddy N.
Mohana Raju K.
Sri Krishnadevaraya University
Abstract
The present work involves the development of curcumin loaded silver hydrogel nanocomposites based on acrylamide and 2-acrylamido-2-methyl propanesulfonic acid, as a template by redox co-polymerization in the presence of hydrophilic crosslinker N,N 1-methylenebisacrylamide. Silver nitrate was taken as the metal precursor and sodium borohydride as a reducing agent. The formation of silver nanoparticles was monitored using UV-Vis absorption spectroscopy. The developed hydrogel silver nanocomposites (HSNC) were characterized by FTIR, UV-Vis, thermogravimetric analysis, scanning electron microscopy and transmission electron microscopy. The curcumin loading and release characteristics were performed for different hydrogel systems. The developed HSNCs were evaluated for preliminary antibacterial applications. © 2012 Springer Science+Business Media, LLC.
Start page
1254
End page
1262
Volume
22
Issue
6
Language
English
OCDE Knowledge area
Ciencia de los polímeros
Scopus EID
2-s2.0-84867690263
Source
Journal of Inorganic and Organometallic Polymers and Materials
ISSN of the container
15741443
Sponsor(s)
Acknowledgments The authors (SR & KMR) thanks the University Grants Commission (UGC-SAP), Government of India, New Delhi for the partial financial support and AFM-B thanks the University of Johannesburg, South Africa for the partial financial support.
Sources of information: Directorio de Producción Científica Scopus