Title
Natural and synthetic cholera toxin antagonists
Date Issued
01 February 2007
Access level
metadata only access
Resource Type
journal article
Author(s)
Velter I.A.
Podlipnik C.
Nicotra F.
Centro de Investigaciones Biológicas, CSIC
Abstract
Cholera Toxin (CT) recognizes the cell membrane through specific interactions with ganglioside GM1. Recent structural elucidation of the CT/GM1 complex has allowed the rational design of artificial receptors for the toxin, which could function as anti-cholera drugs. The efforts towards the rational design of Cholera Toxin inhibitors will be presented. © 2007 Bentham Science Publishers Ltd.
Start page
159
End page
170
Volume
7
Issue
2
Language
English
OCDE Knowledge area
Medicina integral, Medicina complementaria Química orgánica
Scopus EID
2-s2.0-33847782442
PubMed ID
Source
Mini-Reviews in Medicinal Chemistry
ISSN of the container
13895575
Sources of information: Directorio de Producción Científica Scopus