In the world of optimization, especially concerning metaheuristics, solving complex problems represented by applying big data and constraint instances can be difficult. This is mainly due to the difficulty of implementing efficient solutions that can solve complex optimization problems in ad-equate time, which do exist in different industries. Big data has demonstrated its efficiency in solving different concerns in information management. In this paper, an approach based on multiprocessing is proposed wherein clusterization and parallelism are used together to improve the search process of metaheuristics when solving large instances of complex optimization problems, incorporating collaborative elements that enhance the quality of the solution. The proposal deals with machine learning algorithms to improve the segmentation of the search space. Particularly, two different clustering methods belonging to automatic learning techniques, are implemented on bio-inspired algorithms to smartly initialize their solution population, and then organize the resolution from the beginning of the search. The results show that this approach is competitive with other techniques in solving a large set of cases of a well-known NP-hard problem without incorporating too much additional complexity into the metaheuristic algorithms.