Title
Conjunctival intraepithelial and invasive squamous cell carcinomas treated with strontium-90
Date Issued
01 January 1990
Access level
metadata only access
Resource Type
journal article
Author(s)
Clínica Puerta de Hierro
Abstract
Twenty-seven patients with malignant epithelial tumors of the conjunctiva were treated between 1967 and 1987. Histological diagnosis was intraepithelial epithelioma in 15 cases (56%) and squamous cell carcinoma in 12 (44%). All patients were treated with a strontium-90 source on cup-shaped applicators of different sizes according to the extension of the tumor. Surface dose ranged from 60 Gy in a single treatment to 140 Gy in 7 fractions, depending on the thickness of the lesion. Fifteen patients were previously untreated, 7 were irradiated after some type of surgical treatment and 5 were treated for recurrence after multiple surgical excisions. Follow-up period ranged from 2 to 15 years. No patient died of his tumor. There were four local recurrences, three of them in patients with intraepithelial carcinoma. Two of the recurrences were salvaged with a new beta-ray treatment and the other two with enucleation. Since 1981, standard policy was to irradiate the entire conjunctiva in patients with diagnosis of intraepithelial epithelioma. Five patients developed cataracts. Considering the high primary control rate and minimal morbidity, strontium irradiation should be considered as a first-choice treatment for conjunctival tumors. © 1990.
Start page
191
End page
197
Volume
17
Issue
3
Language
English
OCDE Knowledge area
Radiología, Medicina nuclear, Imágenes médicas
Oncología
Subjects
Scopus EID
2-s2.0-0025272608
PubMed ID
Source
Radiotherapy and Oncology
ISSN of the container
01678140
Sources of information:
Directorio de Producción Científica
Scopus