Title
(+)-epi-α-bisbolol is the wound-healing principle of Peperomia galioides: Investigation of the in vivo wound-healing activity of related terpenoids
Date Issued
14 November 2001
Access level
metadata only access
Resource Type
journal article
Author(s)
Marçalo A.
Martin J.
Hammond G.
Abstract
Bioassay-guided investigation of the ethanol extract of Peperomia galioides using a tensile strength method in mice as a monitor led to the isolation of epi-α-bisabolol (1) (ED50 155 μg/mL). An in vivo healing study of selected commercially available monoterpenoids yielded two bioactive compounds, α-bisabolol (2) and α-terpineol (3) (ED50 of 228 and 240 mg/g mouse, respectively).
Start page
1357
End page
1359
Volume
64
Issue
10
Language
English
OCDE Knowledge area
Farmacología, Farmacia
Ciencias de las plantas, Botánica
Scopus EID
2-s2.0-0034752655
PubMed ID
Source
Journal of Natural Products
ISSN of the container
01633864
Sponsor(s)
National Cancer Institute R15CA056911
Sources of information:
Directorio de Producción Científica
Scopus