Title
Cytotoxic triterpene acids from the peruvian medicinal plant Polylepis racemosa
Date Issued
10 July 2000
Access level
metadata only access
Resource Type
journal article
Author(s)
Neto C.
VAISBERG WOLACH, ABRAHAM JAIME
Zhou B.
Kingston D.
Hammond G.
Abstract
Cytotoxicity-guided fractionation of the bark and stem extract of Polylepis racemosa led to the identification of ursolic acid, pomolic acid, 3-O-acetylpomolic acid, and 2-oxopomolic acid. Pomolic acid was the most cytotoxic component, and was specific for M-14 melanoma and ME180 cervical carcinoma, with GI50 values of 6,9 and 8.3/μg/mL respectively.
Start page
483
End page
484
Volume
66
Issue
5
Language
English
OCDE Knowledge area
Farmacología, Farmacia
Ciencias de las plantas, Botánica
Scopus EID
2-s2.0-3242773879
PubMed ID
Source
Planta Medica
ISSN of the container
00320943
Sources of information:
Directorio de Producción Científica
Scopus