The actual behavior of thin RC wall high-rise buildings during an earthquake in Lima, Peru, and the associated seismic loss is unknown. This type of building was assessed done using analytical fragility functions. The numerical model was based on full-scale tests done in Lima, Peru. Nonlinear dynamic response analysis was performed using records simulated for Lima. The damage ratio was estimated for four damage states and fragility functions were obtained assuming that the damage ratio followed log-normal distributions. Seismic performance was evaluated by considering the probability of different damage states for three seismic hazard levels. It was found that highrise buildings present a low probability of collapse in severe earthquakes.