Title
Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru
Date Issued
01 January 2019
Access level
metadata only access
Resource Type
journal article
Author(s)
Rodriguez J.
Quiñones I.
Delgado-De-la-Flor I.
Huanca T.
de la Cruz Perez A.
Publisher(s)
Kasetsart University
Abstract
The objective of this study was to identify genetic single nucleotide polymorphisms (SNPs) in the coding region of the KRTAP11.1 gene from the Suri alpaca population from Puno, Peru. Genomic DNA (n = 119) was used to amplify the 636 bp fragment of the coding region from the KRTAP11.1 gene. The polymerase chain reaction products of the KRTAP11.1 gene were sequenced by both strands and polymorphism type SNPs were identified. All SNPs (n = 3) were in Hardy-Weinberg equilibrium and had a high level of genotypic linkage disequilibrium with the presence of two haplotypes. All genetic polymorphisms generate non-synonymous amino acids changes: SNP 110 T>G (Ser>Ala), SNP 363 T>G (Phe>Cys) and SNP 375 A>C (Tyr>Ser). The results indicated the presence of moderate genetic diversity in the coding region of the KRTAP11.1 gene from the Suri alpaca population.
Start page
87
End page
88
Volume
53
Issue
1
Language
English
OCDE Knowledge area
Zoología, Ornitología, Entomología, ciencias biológicas del comportamiento
Ciencia veterinaria
Genética, Herencia
Subjects
Scopus EID
2-s2.0-85072796597
Source
Agriculture and Natural Resources
ISSN of the container
24681458
Source funding
Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica
Sponsor(s)
This work was supported by the projects “Caracterización de marcadores genéticos de ADN para la conservación, manejo y selección asistida de planteles de alpacas Suri de Puno” [Contract 02-014-2015-OGAJ-UNA-PUNO]” and “Generación de marcadores tipo SNPs en genes codantes de proteínas componentes de la fibra y su uso en selección genética y filogenia de la alpaca” [PROCYT – CONCYTEC]. Genomic data used in this work was provided by the project: “Una aproximación de genómica de poblaciones aplicada a la filogenia y mapeo de rasgos productivos en alpaca” (Contract 19-FINCYT-IA-2013).
Sources of information:
Directorio de Producción Científica
Scopus