Objective: Determine the association between the labor conflicts types and their management in the nursing staff of Honorio Delgado Regional Hospital in Arequipa city, Peru (HRHD). Method: Observational study, cross-sectional, prospective, with quantitative and correlational level approach. The study population was the nursing professionals of Honorio Delgado Espinoza Regional Hospital in Arequipa city, surveyed in 2015. A questionnaire form was used as anonymous measurement tool. We Applied the Thomas Kilmann Test of 30 items, each of which has two options of statements that describe possible response behaviors. A descriptive and association analysis of variables was performed using the Infostat version 2018 software, using the χ2 statistic with significance level p <0.05. Results: The sample was 190 nursing professionals. The results showed a greater number of persons between 50 and 59 years of age, with a percentage of 34.7%, as well as predominance of female staff with 94.7%. The conflicts type most frequent in study population was the Communication-Personnel with 44.8%, leaving in second place the personal conflict with 26.8%, followed by communication conflict with 15.8%. Regarding conflict management, 48.4% considered the cooperative as the most used. No statistically significant association was found between type and conflicts management (χ2 = 13.53, p = 0.139). Conclusions: For nursing staff, there is no relationship between labor conflicts types and the way of management them, however, most of subjects studied consider that Communication-Personnel conflicts are most common and that their management is cooperative.