Biodiesel production from Jatropa Curcas in Peru is interest in the regional government of Tarapoto and other regions of Peru. The advantages of the easy cultivation of this species make it possible to maintain a supply of raw material for the production of biodiesel from Jatropha Curcas with a biorefinery processing perspective. Biodiesel can be produced at small and medium scale, having the potential to be an option for energy supply in isolated rural areas, especially in the Amazon rainforest. With the local production of biodiesel, the standard of living in rural communities can be improved, reducing migrations and fixing the rural population in the countryside. Transesterification reaction defined the production of biodiesel. Actually, concept of biorefinery in important for new plants of biodiesel. Where all waste (pulp of fruit, shell and cake) is used. The pulp of the fruit, the shell of the seed and the cake resulting from the extraction of the oil (which contains 56% of proteins), can be used for organic fertilization or for the production of more energy. We obtained biodiesel of Jatropha oil at 60°C in 40 minutes. The production of biodiesel is an option to replace other raw materials.