Introduction:On certain occasions work exposes us to common risks, such as food poisoning; This may be due to exposure to unhealthy places of sale, especially in Peru, which still has a poor health system. Objective: To determine whether the type of employment is a risk factor for the diarrhea among workers in fourteen cities in Peru. Materials and Methods: Retrospective and multicenter cohort study. Investigated diarrhea among workers attending their occupational appointments in fourteen cities in Peru.This was associated with the type of work performed. Statistical association was obtained using the generalized linear models. Results: Of the 4057 respondents, 39% had at least one episode of diarrhea in the past year. There was an increased risk of diarrhea in the last year among workers; on the other hand, the risk of employees of mining companies decreased, trade, outsourced transport or the education sector; adjusted for age, type of instruction and daily hygiene. Conclusion: Some types of work generate different risks for the diarrhea, this must be monitored and controlled, since it could have repercussions for the worker and the labor institution.