Background: According to the World Health Organization obesity chronic disease is the most common transmissible but are isolated studies on obesity and its characterization in women in Cuba. Objective: To determine some characteristics of obese women of 20-59 years of the town Holguin, Cuba. Methods: A cross-sectional study was conducted between February 2012 and June 2013 in obese women of 20-59 years of the offices of the 10 health areas in the municipality Holguin. The sample was probabilistic using random cluster sampling were selected 300 obese women. Measured: body weight, height, waist circumference, hip circumference, skinfold (biceps, triceps, suprailiac and subscapular). Other variables: age and associated diseases. Survey for lifestyle (physical activity, dietary habits, demographic characteristics). Lipid profile: total cholesterol, triglycerides and LDL Results: There is a predominance of android obesity (85.7 %) and post-pubertal obesity (68.0%). From the viewpoint of most obese causal exogenous (87.3%). Only 8% systematic physically active. More than half of the obese have increased the lipid profile: total cholesterol (58.7%), triglycerides (66.0%), LDL (63.7%). It was found a poor distribution of the portions during the day. Conclusions: To reduce obesity in women of 20-59 years Holguin municipality is required to modify lifestyles.