Ventilation systems are used in order to provide an appropriate temperature inside buildings. For this reason, convection heat transfer is achieved by fans and extractors to produce wind flows. Nevertheless, fans are loud in operation, therefore passive or active mechanisms are used to reduce the noise level inside buildings. However, passive mechanisms are costly and need big space to be fixed around the ventilation system to absorb noise compared to Active Noise Control (ANC). ANC systems are being employed to avoid big costs and space requirements. Accordingly, strategies and algorithms for active noise reduction were analyzed, implemented and tested experimentally in this paper for applications in duct ventilation systems. Algorithms implemented were simulated by Matlab software. Piezo actuator was utilized as an active element of ANC system during experimental testings.