In this work, we report results of lead sulfide (PbS) quantum dots (QDs) luminescence spectra evolution during the QDs spread process around the core of silica microstructured optical fibers (MOFs). These QDs are excited, via evanescent field effect, with a 532nm or 785nm laser guided by the MOF cores. The PbS-core QDs of different sizes (originally immersed in Toluene) with emission bands around 877 nm (PbS877), 1160 nm (PbS1160) and 1474 nm (PbS1474) were inserted inside the silica MOF structure by using an N2 gas pressure system. The broadband luminescence spectra varying from around 1000 nm to 1600 nm were obtained by using QDs mixtures spread around MOF core surfaces. This QDs spread technique and the PbS QDs broadband luminescence spectra results could have potential applications in optical amplifier,sensor and nonlinear optical fiber loop mirror devices. © 2010 SPIE.