The rapid increase of the area cultivated with asparagus in Ica generated a pressure for opening new lands to agriculture. The following research was conducted to evaluate the effect of long-term asparagus management on properties of a desert soil. Soil chemical properties and crop biometrical parameters were measured in alternate years in a commercial asparagus field in Ica. Asparagus fertilization affected soil pH and levels of available P and K. Little effect was observed on soil organic matter. Drip irrigation increased soil salinity after 10 years. Plant size and foliar dry matter decreased slightly but the number of stems increased progressively. The nutrient content was adequate through the evaluation period. Intensive asparagus production can be performed while in the meantime increasing soil quality.