Title
Improving the efficiency of MECoMaP: A protein residue-residue contact predictor
Date Issued
01 December 2013
Access level
open access
Resource Type
conference paper
Author(s)
Universidad Pablo de Olavide
Universidad de Ciego de Ávila
Abstract
This work proposes an improvement of the multi-objective evolutionary method for the protein residue-residue contact prediction called MECoMaP. This method bases its prediction on physicochemical properties of amino acids, structural features and evolutionary information of the proteins. The evolutionary algorithm produces a set of decision rules that identifies contacts between amino acids. These decision rules generated by the algorithm represent a set of conditions to predict residue-residue contacts. A new encoding used, a fast evaluation of the examples from the training data set and a treatment of unbalanced classes of data were considered to improve the the efficiency of the algorithm. © Springer-Verlag 2013.
Start page
166
End page
173
Volume
8259 LNCS
Issue
PART 2
Language
English
OCDE Knowledge area
Ciencias de la computación Bioinformática
Scopus EID
2-s2.0-84893158248
Resource of which it is part
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
ISSN of the container
16113349
ISBN of the container
978-364241826-6
Conference
18th Iberoamerican Congress on Pattern Recognition, CIARP 2013
Sources of information: Directorio de Producción Científica Scopus