Title
The role of immune reconstitution inflammatory syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy
Date Issued
01 April 2005
Access level
open access
Resource Type
journal article
Author(s)
Shelburne S.
Darcourt J.
Greenberg S.
Hamill R.
Atmar R.
Visnegarwala F.
Baylor College of Medicine
Publisher(s)
Oxford University Press
Abstract
This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis. © 2005 by the Infectious Diseases Society of America. All rights reserved.
Start page
1049
End page
1052
Volume
40
Issue
7
Language
English
OCDE Knowledge area
Enfermedades infecciosas
Scopus EID
2-s2.0-15744394140
PubMed ID
Source
Clinical Infectious Diseases
ISSN of the container
10584838
Sponsor(s)
We thank Dr. Thomas Giordano and Dr. Robert Lasky for assistance with statistical analysis. Financial support. Bristol-Myers Squibb (HIV fellowship grant to S.A.S.) and the National Institute of Allergy and Infectious Diseases (fellowship grant T32-AI055413 to S.A.S.). Potential conflicts of interest. All authors: no conflicts.
Sources of information: Directorio de Producción Científica Scopus