This paper presents estimates for potato demand, supply and trade in South America to the year 2030 according to three scenarios: baseline, high demand and limited supply. The results highlight the importance of Brazil with its massive population and low per capita consumption of potato as a key driver of regional outcomes. According to the baseline and high demand scenarios, improved productivity in Andean countries such as Ecuador and Colombia will influence output and consumption increases in those locations as well. The potential adverse effects of the advent of climate change on the potato sector in more vulnerable growing areas in the region will result in much more modest increases in output in those locations according to the low supply scenario. While domestic potato marketing will continue to expand, foreign trade in potatoes remains small in absolute terms and as a percentage of national and sub-regional output. The findings call attention to opportunities for agribusiness initiatives in input markets as well as for both fresh and processed potato products for human consumption in the decades ahead.