This communication summarizes the use of double-skinned membranes for hydrogen separation in presence of TiO2 based catalyst (PtReCe/TiO2). The use of this type of membrane avoids the direct contact between catalyst particles and surface of the Pd-based hydrogen selective layer due to the presence of a mesoporous YSZ/γ-Al2O3 layer. The PdAg layer is protected by the mesoporous layer from direct contact with catalyst particles, avoiding erosion and possible chemical interactions. In comparison with a conventional PdAg membrane, the hydrogen flux of DS-membrane was observed not to be compromised during test carried out at 400 °C.