Title
Green propolis: Thirteen constituents of polar extract and total flavonoids evaluated during six years through RP-HPLC
Date Issued
01 December 2015
Access level
metadata only access
Resource Type
journal article
Author(s)
De Figueiredo S.M.
Binda N.S.
De Moura Almeida B.
Abreu S.R.L.
De Abreu J.A.S.
Pastore G.M.
Sato H.H.
Toreti V.C.
Park Y.K.
Filho S.A.V.
Caligiorne R.B.
Universidade Estadual de Campinas
Publisher(s)
Bentham Science Publishers
Abstract
In order to verify the chemical qualities of polar extract of Green Propolis produced in the State of Minas Gerais, Brazil, was analyzed by means of RP-HPLC, the concentration of eleven flavonoids, Artepillin C and p-coumaric acid were analyzed by means of RP-HPLC. Samples were collected in the months of February, March, May, July, September, and October, during a period of six years (2008 to 2013) and the results compared with purchased standards. Artepillin C was the main constituent (80-90%) found in all samples. Lower concentrations of p-coumaric acid, chrysin and kaempferide were observed in March, and of ricin and galangin in September. Respectively, these months correspond to the end of Summer and Spring period in Brazil. The variation in concentration of the analyzed constituents always occurred in the same month, during the entire six years of evaluation period. All thirteen constituents of Green Propolis were detected throughout the study period, and the average concentration of each one was similar in relation to the respective monthly collection period of each year. Due to similarities among chemical constituents of Green Propolis with those present in B. dracuncufolia, this plant was identified as being the principal source of Green Propolis.
Start page
229
End page
239
Volume
12
Issue
4
Language
English
OCDE Knowledge area
Ingeniería de producción
Farmacología, Farmacia
Subjects
Scopus EID
2-s2.0-84958656936
PubMed ID
Source
Current Drug Discovery Technologies
ISSN of the container
15701638
Sponsor(s)
Funding text
The authors thank the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG) for financial support.
Sources of information:
Directorio de Producción Científica
Scopus