cris.boxmetadata.label.title
Decline in sulfadoxine-pyrimethamine-resistant alleles after change in drug policy in the Amazon region of Peru
cris.boxmetadata.label.dateissued
01 browse.startsWith.months.february 2008
cris.boxmetadata.label.accesslevel
open access
cris.boxmetadata.label.resourcetype
journal article
cris.boxmetadata.label.authors
Zhou Z.
Griffing S.M.
De Oliveira A.M.
McCollum A.M.
Quezada W.M.
Escalante A.A.
Udhayakumar V.
cris.boxmetadata.label.abstract
The frequency of alleles with triple mutations conferring sulfadoxine-pyrimethamine (SP) resistance in the Peruvian Amazon Basin has declined (16.9% for dhfr and 0% for dhps compared to 47% for both alleles in 1997) 5 years after SP was replaced as the first-line treatment for Plasmodium falciparum malaria. Microsatellite analysis showed that the dhfr and dhps alleles are of common origin. Copyright © 2008, American Society for Microbiology. All Rights Reserved.
cris.boxmetadata.label.citationstartpage
739
cris.boxmetadata.label.citationendpage
741
cris.boxmetadata.label.volume
52
cris.boxmetadata.label.issue
2
cris.boxmetadata.label.language
English
cris.boxmetadata.label.ocdeknowledgeArea
Farmacología, Farmacia
Parasitología
cris.boxmetadata.label.doi
cris.boxmetadata.label.scopusidentifier
2-s2.0-38649109842
cris.boxmetadata.label.pubmedidentifier
cris.boxmetadata.label.source
Antimicrobial Agents and Chemotherapy
cris.boxmetadata.label.containerissn
00664804
peru-layout.shadow-copies
Directorio de Producción Científica
Scopus