Title
Cordiosides A and B, two new 19-hydroxy-29-norlanostane glycosides isolated from the flowers of Cordia lutea
Date Issued
01 December 2022
Access level
open access
Resource Type
journal article
Publisher(s)
Elsevier Ltd
Abstract
We present here the isolation and structural characterization of two undescribed mono-glycosylated triterpenes with a 19-hydroxy-29-norlanostane core. These compounds (1-2) were isolated from an ethanolic extract of the dried flowers of Cordia lutea, a widely used Peruvian traditional medicine. Their structures were determined by examination of their NMR and MS data. For compound 1, its structure was confirmed by single crystal X-ray structural analyses. 1 showed moderate activity against Helicobacter pylori (MIC = 15.6 µg/mL), and was not active against Escherichia coli, Pseudomonas aeruginosa or Staphylococcus aureus (MIC > 125 µg/mL).
Start page
40
End page
44
Volume
52
Language
English
OCDE Knowledge area
Ciencias de las plantas, Botánica Farmacología, Farmacia
Scopus EID
2-s2.0-85138032140
Source
Phytochemistry Letters
ISSN of the container
18743900
Sponsor(s)
IC thanks the Institut de Recherche pour le Développement of France ( IRD ) for the award of a grant (Allocation de Recherche pour une Thèse au Sud, ARTS), and the Peruvian Council of Science ( CONCYTEC ) for previous funding. This work also benefited from the funding of the LMI LAVI (International joint Laboratory, IRD-UPCH) by the IRD. These sources of funding had no role in study design; collection, analysis and interpretation of data; writing of the report; and the decision to submit the article for publication.
Sources of information: Directorio de Producción Científica Scopus